生育健康流行病学

出生缺陷、早产等不良妊娠结局的环境病因及机制研究

1. 北京市自然科学基金面上项目，孕早期血清铜水平与妇女脂质代谢及自发性早产发生风险关系的研究（7222248），2022/01-2024/12，主持

2. 国家自然科学金面上项目，多环芳烃复合暴露致胎儿神经管缺陷的协同效应及毒性机制研究（81973056），2020/01-2023/12，主持     

3. 科技部重点研发计划应急专项课题，新冠肺炎流行对孕妇不良妊娠结局的影响（2020YFC0846300），2020/04-2021/06，主持

4. 国家自然科学基金面上项目，多环芳烃诱发自发性早产的效应与机制以及叶酸的保护作用（81673177），2017/01-2020/12，主持

5. 国家自然科学基金中英交流项目，神经管缺陷的重要环境和遗传因素（81511130088），2015/04-2017/12，主持

6. 国家自然科学基金面上项目，孕早期被动吸烟致胎儿神经管缺陷发生的风险及机制研究（81373014），2014/01-2017/12，主持

7. 科技部国家重点研发计划课题，环境和表观遗传变化在结构性出生缺陷发生中的作用和致病机制（2021YFC2701001），2021/12-2024/11，骨干

8. 科技部国家重点研发计划课题，环境因素导致重要器官发育异常的关键环节（2016YFC1000501），2016/07-2021/06，骨干

1. Xu R, Meng X, Pang Y, An H, Wang B, Zhang L, Ye R, Ren A, Li Z*, Gong J*. Associations of maternal exposure to 41 metals/metalloids during early pregnancy with the risk of spontaneous preterm birth: Does oxidative stress or DNA methylation play a crucial role? Environ Int. 2022 Jan;158:106966. SCI收录IF2021= 9.621/Q1；

2. Jia X, Zhang L, Zhao J, Ren M, Li Z, Wang J, Wang S, Liu Y, An H, Li Y, Yan L, Li Z*, Liu X*, Pan B*, Ye R. Associations between endocrine-disrupting heavy metals in maternal hair and gestational diabetes mellitus: A nested case-control study in China. Environ Int. 2021 Dec;157:106770. SCI收录IF2021= 9.621/Q1；

3. Ren M, Jia X, Shi J, Yan L, Li Z, Lan C, Chen J, Li N, Li K, Huang J, Wu S, Lu Q, Li Z*, Wang B*, Liu J. Simultaneous analysis of typical halogenated endocrine disrupting chemicals and metal(loid)s in human hair. Sci Total Environ. 2020 May 20;718:137300. SCI收录IF2019= 6.5519/Q1；

4. Liu J, Li Z*, Ye R, Ren A, Liu J. Folic acid supplementation and risk for congenital limb reduction defects in China. Int J Epidemiol. 2019 Dec 1;48(6):2010-2017.SCI收录IF2019 = 7.339/Q1；

5. Yu Y, Gao M, Wang X, Guo Y, Pang Y, Yan H, Hao Y, Zhang Y, Zhang L, Ye R, Wang B*, Li Z*. Recommended acceptable levels of maternal serum typical toxic metals from the perspective of spontaneous preterm birth in Shanxi Province, China. Sci Total Environ. 2019 Oct 10;686:599-605. SCI收录IF2019= 6.5519/Q1；

6. Wang B#*, Zhu Y#, Yan L, Zhang J, Wang X, Cheng H, Li Z*, Ye R, Ren A. Association of maternal chronic arsenic exposure with the risk of neural tube defects in Northern China. Environ Int. 2019 May;126:222-227. SCI收录IF2019= 7.943/Q1；

7. Li Z, Wang B*, Huo W, Liu Y, Zhu Y, Xie J, Li Z*, Ren A. Are concentrations of alkaline earth elements in maternal hair associated with risk of neural tube defects? Sci Total Environ. 2017 Dec 31;609:694-700. SCI收录IF2017 =4.900/Q1；

8. Huo W, Zhu Y, Li Z, Pang Y, Wang B, Li Z*. A pilot study on the association between rare earth elements in maternal hair and the risk of neural tube defects in north China. Environ Pollut. 2017 Jul; 226:89-93. SCI收录IF2017 = 5.099/Q1；

9. Li Z, Mei Z, Zhang L, Li H, Zhang Y, Li N, Ye R, Ren A, Liu JM, Serdula MK. Effects of Prenatal Micronutrients Supplementation on Spontaneous Preterm Birth: Double-Blind Randomized Controlled Trial in China. Am J Epidemiol. 2017 Aug 1;186(3):318-325. SCI收录IF2017 = 4.825/Q1；

10. Li Z, Ye R, Zhang L, Li H, Liu J, Ren A. Periconceptional folic acid supplementation and the risk of preterm births in China: a large prospective cohort study. Int J Epidemiol. 2014 Aug;43(4):1132-9.  SCI收录IF2014 = 9.197/Q1；