1. 免疫毒理学
2. 分子与细胞毒理学
3. 环境污染物
4. 药物毒理
5. 生物活性物质的免疫调节作用
6. 安全性评价和风险评估
1. 国家自然科学基金 老化黑碳所致呼吸道炎症中的铁蛋白——IL-33相关毒性作用通路研究
2. 国家重点研发计划“基于毒作用机制和健康效应终点的食品稀土元素和添加剂的安全性评估”
3. 国家科技支撑项目“男用避孕方法的研究——LTQ药物抗生育作用过程中相关毒理研究”
4. 国际铜业协会“铜过量对机体免疫系统影响”;
5. 国家自然科学基金重大项目“二次颗粒物和臭氧的环境暴露和健康效应”
6. 国家自然科学基金重大项目“稀土农用的环境化学行为及生态、毒效应”
7. 国家重大新药创制-安全性评价技术平台;
8. 十一五科技支撑计划重大项目“食品安全关键技术-农药及内分泌干扰物的复合效应评估技术研究”;
1. Jianhong Ge, Hongqian Chu, Qianqian Xiao, Weidong Hao, Jing Shang, Tong Zhu, Zhaogang Sun, Xuetao Wei*. BC and 1,4NQ-BC up-regulate the cytokines and enhance IL-33 expression in LPS pretreatment of human bronchial epithelial cells. Environ Pollut. 2021, 273:116452
2. Qianqian Xiao, Yiming Song, Hongqian Chu, Mengmeng Tang, Jianjun Jiang, Qinghe Meng, Weidong Hao, Xietao Wei*. 1,4NQ-BC enhances the lung inflammation by mediating the secretion of IL-33 which derived from macrophages. Environ Pollut. 2020, 265(Pt A):114729
3. Kang Chen1, Xuetao Wei1, Jian Zhang, Raghunath Pariyani, Johanna Jokioja, Maaria Kortesniemi, Kaisa M Linderborg, Jari Heinonen, Tuomo Sainio, Yumei Zhang, Baoru Yang. Effects of Anthocyanin Extracts from Bilberry (Vaccinium myrtillus L.) and Purple Potato (Solanum tuberosum L. var. 'Synkeä Sakari') on the Plasma Metabolomic Profile of Zucker Diabetic Fatty Rats. J Agric Food Chem. 2020, 68(35): 9436-9450.
4. Siqi Wang, Feifei Wang, Lixin Yang, Qin Li, Yao Huang, Zhiyuan Cheng, Hongqian Chu, Yiming Song, Lanqin Shang, Weidong Hao, Xuetao Wei*. Effects of coal-fired PM 2.5 on the expression levels of atherosclerosis-related proteins and the phosphorylation level of MAPK in ApoE -/- mice. BMC Pharmacol Toxicol. 2020, 21(1):34.
5. Hongqian Chu, Xi Tao, Zhaogang Sun, Weidong Hao, Xuetao Wei *. Galactooligosaccharides Protects Against DSS-induced Murine Colitis Through Regulating Intestinal Flora and Inhibiting NF-κB Pathway, Life Sciences, 2020, 242: 117220
6. Zhiyuan Cheng, Hongqian Chu, Siqi Wang, Yao Huang, Xiaohong Hou, Qi Zhang, Wenjuan Zhou, Lixia Jia, Qinghe Meng, Lanqing Shang, Yiming Song, Weidong Hao, Xuetao Wei*. TAK1 knock-down in macrophage alleviate lung inflammation induced by black carbon and aged black carbon. Environ Pollut. 2019, 253:507-515.
7. Hongqian Chu, Weidong Hao, Zhiyuan Cheng, Yao Huang, Siqi Wang, Jing Shang, Xiaohong Hou, Qinghe Meng, Qi Zhang, Lixia Jia, Wenjuan Zhou, Pengmin Wang, Guang Jia, Tong Zhu, Xuetao Wei*. Black carbon particles and ozone-oxidized black carbon particles induced lung damage in mice through an interleukin-33 dependent pathway, Science of the Total Environment, 2018, 644:217-228.
8. Zhiyuan Cheng, Jianjun Jiangb, Xiaohua Yang, Hongqian Chu, Ming Jin, Yuan Li, Xi Tao, Siqi Wang, Yao Huang, Lanqin Shang, Shuang Wu , Weidong Hao, Xuetao Wei*. The Research of Genetic Toxicity of β-phellandrene, Environmental Toxicology and Pharmacology, 2017, 54:28-33
9. Hongqian Chu, Jing Shang, Ming Jin, Yueyue Chen, Yao Pan, Yuan Li, Xi Tao, Zhiyuan Cheng, Qinghe Meng, Qian Li, Guang Jia, Tong Zhu, Weidong Hao*, Xuetao Wei*. Comparison of lung damage in mice exposed to black carbon particles and 1,4-naphthoquinone coated black carbon particles, Science of the Total Environment, 2017, 580:572-581
10. Siqi Wang, Haifeng Jin, Qiuqing Tang, Jun Fu, Zeming Ren, Cike Peng, Lanqin Shang, Weidong Hao, Xuetao Wei*. The effect of ethephon on immune system in male offspring of mice, Environmental Toxicology and Pharmacology, 2017, 49:119-123.