Reproductive health epidemiology

1. the National Natural Science Foundation of China，82173527, Study on the relationships between exposure to rare earth elements during pregnancy and the risk of hypertensive disorders of pregnancy and their mechanisms, 2022/01-2025/12，under study，Core-Investigator

2. Data mining of pre-implantation genetic testing, 2021/06-2025/05, under study，Principal -Investigator

3. Risk sources of agricultural products and road dust exposure in Haojia river area(sub-project)，2020/09-2020/12，completed，Principal -Investigator

4. Ministry of Science and Technology, China National Key R&D Program, 2020YFC0846300, Association between novel coronavirus pneumonia and adverse pregnancy outcomes, 2020/04-2020/12, completed，Core-Investigator

5. the National Natural Science Foundation of China，41771527, In vitro and body levels of polycyclic aromatic hydrocarbons among women of childbearing age at an typical area in north China，2018/01-2021/12，completed，Co-Investigator

6. the National Natural Science Foundation of China，31371523，Effects on fetus NTDs causing by polycyclic aromatic hydrocarbons and its mechanism of oxidative stress，2014/01-2017/12，completed，Co-Investigator

7. the National Science & Technology Pillar Program，2013BAI12B00，Research on key technologies and applications of primary prevention of birth defects before pregnancy，2013/01-2015/12，completed，Co-Investigator

1. Yushan Du, Shuangbo Xia, Jinjuan Zhang, Le Zhang*, Jufen Liu*. Plasma folate deficiency increases the risk for abnormal blood pressure in Chinese women of childbearing age. Nutrition Research, 2021, https://doi.org/10.1016/j.nutres.2021.12.003.

2. Song Q, Wei J, Wang J, Zhang L*, Liu X*, Zhang Y, Li N, Li Z. Rate of Correct Use of Folic Acid Supplementation Among Pregnant Women - Beijing Municipality, China, 2017-2019. China CDC Wkly. 2021 Sep 10;3(37):783-787.

3. Jia X, Zhang L#, Zhao J, Ren M, Li Z, Wang J, Wang S, Liu Y, An H, Li Y, Yan L, Li Z*, Liu X*, Pan B*, Ye R. Associations between endocrine-disrupting heavy metals in maternal hair and gestational diabetes mellitus: A nested case-control study in China. Environ Int. 2021 Dec;157:106770. doi: 10.1016/j.envint.2021.106770. Epub 2021 Jul 24. PMID: 34314978.

4. Xiaoqian Jia, Mengyuan Ren, Yali Zhang, Rongwei Ye, Le Zhang *, Zhiwen Li*. Association between tea drinking and plasma folate concentration among women aged 18-30 years in China. Public Health Nutrition: 4929-4936.

5. Zhang L, Zhang Y#, Li Z*, Ren A, Liu J, Ye R*. Maternal periconceptional body mass index and risk for neural tube defects: results from a large cohort study in China. J Matern Fetal Neonatal Med. 2021 Jan;34(2):274-280.

6. Yongxiu Hao, Yiming Pang, Huina Yan, Yali Zhang, Jufen Liu, Lei Jin, Lailai Yan, Da Chen, Ligang Hu, Qian Liu, Yanan Qin, Bin Wang, Zhiwen Li, Rongwei Ye *, Le Zhang *, Aiguo Ren, Association of maternal serum copper during early pregnancy with the risk of spontaneous preterm birth: a nested case-control study in China, Environ Int, 2019,122:237-243.

7. Huina Yan, Zhan Wang, Jiamei Wang, Xiaohong Liu, Le Zhang*. [Survey on caffeine exposure among pregnant women in high intellectual area of Beijing]. Chinese Journal of Health Education,2017,33(11):1005-1007,1015.

8. Meng Fanwen, Chen Sen, Liu Yashan, Li Nan, Yang Na, Liu Yingjuan, Zhang Le*, Ye Rongwei*. [Incidence and risk factors of hypertensive disorders complicating pregnancy in 5 counties of Hebei province]. Chinese Journal of Reproductive Health, 2015, 26(2): 112-115..

9. Le Zhang, Meiping Sun, Weixian Gao, Shixin Hong, Yali Zhang*. [Prenatal screening for major fetal heart defects by training sonographers in township hospitals and county health centers: a feasibility study]. Journal of Peking University( Health Sciences), 2014, 46(03):373-378.

10.    Le Zhang, Aiguo Ren*, Zhiwen Li, Ling Hao, Yihua Tian, Zhu Li. Folate concentrations and folic acid supplementation among women in their first trimester of pregnancy in a rural area with a high prevalence of neural tube defects in Shanxi, China. Birth Defects Res A, 2006, 76(6): 461-466.